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Excluding the patients with retinitis and central nervous system disease, the rate of sight-threatening complications in our series was lower than expected.Almost one third of study patients had no ocular complications or only mild surface epithelial disease.Although the relatively low incidence of sight-threatening disease in our study population may have been a consequence of aggressive management with acyclovir,chronic infectious pseudodendritic keratitis,retinitis,and central nervous system disease, complications of ophthalmic zoster whose pathogenesis is largely a consequence of active viral replication,were particularly devastating and difficult to manage. |
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